The RNA AI company redefining RNA design.
THE TEAM
A team of seasoned operatives joined forces with leading investigators in RNA biology and AI to build a category defining RNA design company.
Nazli Azimi
Co-Founder & CEO
Sasan Amini
Co-Founder
Hani Goodarzi
Scientific Co-Founder
Timo Hagen
Director of RNA Research, Founding Scientist
Kian Yousefi
Director of Translational Research, Founding Scientist
With more than a decade of research, Therna’s founders are at the forefront of regulatory RNA biology, authoring several acclaimed publications.
IN THE PRESS:
THE MODEL
Therna is pioneering a new era of programmable RNA therapeutics by integrating deep RNA biology with generative AI. Our platform explores RNA sequence space beyond natural boundaries to design custom mRNAs with enhanced translational efficiency, tissue specificity, durability, and reduced immunogenicity.
THE PROCESS
LAB IN THE LOOP
LAB IN THE LOOP
Our iterative pipeline seamlessly combines biology and computation: AI generates novel RNA sequences, lab experiments validate them, and results are used to retrain the model, enhancing its predictive capabilities.
THE APPROACH
Our approach to mRNA design is comprehensive:
We consider the entire mRNA molecule within various cellular contexts, regulatory components, thereby its full complexity into account.
This integrated, AI-powered strategy enables us to re-write the “grammar” of mRNA achieving properties previously unfeasible with other treatment modalities, such as improved translation and stability, and precise tissue specificity.
